BAIT
TIA1
2310050N03Rik, AI256674, TIA-1, mTIA-1
cytotoxic granule-associated RNA binding protein 1
GO Process (3)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ADD1
AI256389
adducin 1 (alpha)
GO Process (14)
GO Function (8)
GO Component (14)
Gene Ontology Biological Process
- actin filament bundle assembly [ISO]
- barbed-end actin filament capping [ISO]
- cell morphogenesis [IMP]
- cell volume homeostasis [IMP]
- cellular response to retinoic acid [ISO]
- erythrocyte differentiation [IMP]
- hemoglobin metabolic process [IMP]
- homeostasis of number of cells within a tissue [IMP]
- in utero embryonic development [IMP]
- multicellular organism growth [IMP]
- negative regulation of actin filament polymerization [ISO]
- positive regulation of angiogenesis [ISO]
- positive regulation of endocytosis [ISO]
- positive regulation of protein binding [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- F-actin capping protein complex [ISO]
- cell [IMP]
- cytoskeleton [IDA]
- dendrite [ISO]
- dendritic spine [ISO]
- focal adhesion [ISO]
- intermediate filament cytoskeleton [ISO]
- membrane [IDA]
- nucleoplasm [ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- postsynaptic density [ISO]
- synapse [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.
Dendritic mislocalization of microtubule associated protein tau is a hallmark of tauopathies, but the role of dendritic tau is unknown. We now report that tau interacts with the RNA-binding protein (RBP) TIA1 in brain tissue, and we present the brain-protein interactome network for TIA1. Analysis of the TIA1 interactome in brain tissue from wild-type (WT) and tau knockout mice demonstrates ... [more]
Cell Rep Dec. 17, 2015; 15(7);1455-1466 [Pubmed: 27160897]
Throughput
- High Throughput
Curated By
- BioGRID