BAIT

APEX1

APE, APE1, APEN, APEX, APX, HAP1, REF1
APEX nuclease (multifunctional DNA repair enzyme) 1
Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

Antoniali G, Serra F, Lirussi L, Tanaka M, D'Ambrosio C, Zhang S, Radovic S, Dalla E, Ciani Y, Scaloni A, Li M, Piazza S, Tell G

Mammalian apurinic/apyrimidinic endonuclease 1 is a DNA repair enzyme involved in genome stability and expression of genes involved in oxidative stress responses, tumor progression and chemoresistance. However, the molecular mechanisms underlying the role of apurinic/apyrimidinic endonuclease 1 in these processes are still unclear. Recent findings point to a novel role of apurinic/apyrimidinic endonuclease 1 in RNA metabolism. Through the characterization ... [more]

Nat Commun Dec. 06, 2016; 8(1);797 [Pubmed: 28986522]

Throughput

  • High Throughput

Curated By

  • BioGRID