BAIT
TRIM44
DIPB, HSA249128, MC7
tripartite motif containing 44
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
ENO1
ENO1L1, MPB1, NNE, PPH
enolase 1, (alpha)
GO Process (9)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- gluconeogenesis [TAS]
- glucose metabolic process [TAS]
- glycolytic process [TAS]
- negative regulation of cell growth [IDA]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- negative regulation of transcription, DNA-templated [IDA]
- response to virus [IEP]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4.
There is growing evidence that tripartite motif-containing protein 44 (TRIM44) plays crucial role in tumor development. However, the underlying mechanism of this deubiquitinating enzyme remains unclear.Large clinical samples were used to detect TRIM44 expression and its associations with clinicopathological features and prognosis. Gain- and loss-of-function experiments in cell lines and mouse xenograft models were performed to elucidate the function and ... [more]
J. Exp. Clin. Cancer Res. Mar. 28, 2019; 38(1);137 [Pubmed: 30922374]
Throughput
- High Throughput
Curated By
- BioGRID