BAIT

DUXAP9

double homeobox A pseudogene 9
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

SAMD9

C7orf5, DRIF1, NFTC, OEF1, OEF2
sterile alpha motif domain containing 9
GO Process (0)
GO Function (1)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

LncRNA DUXAP9-206 directly binds with Cbl-b to augment EGFR signaling and promotes non-small cell lung cancer progression.

Zhu T, An S, Choy MT, Zhou J, Wu S, Liu S, Liu B, Yao Z, Zhu X, Wu J, He Z

Long noncoding RNAs (lncRNAs) are involved in the pathology of various tumours, including non-small cell lung cancer (NSCLC). However, the underlying molecular mechanisms of their specific association with NSCLC have not been fully elucidated. Here, we report that a cytoplasmic lncRNA, DUXAP9-206 is overexpressed in NSCLC cells and closely related to NSCLC clinical features and poor patient survival. We reveal ... [more]

J. Cell. Mol. Med. Mar. 01, 2019; 23(3);1852-1864 [Pubmed: 30515972]

Throughput

  • High Throughput

Additional Notes

  • assayed using RIP (RNA immunoprecipitation) with DUXAP9-206 RNA as bait, pulling down the indicated hit proteins

Curated By

  • BioGRID