BAIT
HPSE
HPA, HPA1, HPR1, HPSE1, HSE1
heparanase
GO Process (12)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- cell-matrix adhesion [IDA]
- glycosaminoglycan catabolic process [TAS]
- glycosaminoglycan metabolic process [TAS]
- heparan sulfate proteoglycan catabolic process [IDA]
- positive regulation of blood coagulation [IDA]
- positive regulation of osteoblast proliferation [IDA]
- positive regulation of protein kinase B signaling [IDA]
- positive regulation vascular endothelial growth factor production [IDA]
- proteoglycan metabolic process [TAS]
- regulation of hair follicle development [IDA]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DNAJA1
DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2, RP11-54K16.1
DnaJ (Hsp40) homolog, subfamily A, member 1
GO Process (9)
GO Function (7)
GO Component (5)
Gene Ontology Biological Process
- negative regulation of JUN kinase activity [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of protein ubiquitination [IDA]
- positive regulation of apoptotic process [IMP]
- protein folding [TAS]
- protein localization to mitochondrion [IMP]
- protein refolding [IBA]
- regulation of protein transport [IDA]
- response to unfolded protein [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
Interferon-stimulated genes (ISGs) form the backbone of the innate immune system and are important for limiting intra- and intercellular viral replication and spread. We conducted a mass-spectrometry-based survey to understand the fundamental organization of the innate immune system and to explore the molecular functions of individual ISGs. We identified interactions between 104 ISGs and 1,401 cellular binding partners engaging in ... [more]
Nat. Immunol. Dec. 01, 2018; 20(4);493-502 [Pubmed: 30833792]
Throughput
- High Throughput
Curated By
- BioGRID