BAIT
MICB
PERB11.2, DAAP-210H10.1
MHC class I polypeptide-related sequence B
GO Process (10)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- T cell mediated cytotoxicity [IBA]
- antigen processing and presentation [IBA]
- gamma-delta T cell activation [IDA]
- immune response-activating cell surface receptor signaling pathway [IDA]
- natural killer cell mediated cytotoxicity [IBA]
- negative regulation of defense response to virus by host [IDA]
- regulation of immune response [TAS]
- response to heat [IDA]
- response to oxidative stress [IDA]
- response to retinoic acid [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CLTA
LCA
clathrin, light chain A
GO Process (7)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- axon guidance [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- membrane organization [TAS]
- negative regulation of epidermal growth factor receptor signaling pathway [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- post-Golgi vesicle-mediated transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
Interferon-stimulated genes (ISGs) form the backbone of the innate immune system and are important for limiting intra- and intercellular viral replication and spread. We conducted a mass-spectrometry-based survey to understand the fundamental organization of the innate immune system and to explore the molecular functions of individual ISGs. We identified interactions between 104 ISGs and 1,401 cellular binding partners engaging in ... [more]
Nat. Immunol. Dec. 01, 2018; 20(4);493-502 [Pubmed: 30833792]
Throughput
- High Throughput
Curated By
- BioGRID