BAIT

SAMD4A

SAMD4, SMAUG, SMAUG1, SMG, SMGA
sterile alpha motif domain containing 4A
GO Process (2)
GO Function (2)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens
PREY

BASP1

CAP-23, CAP23, NAP-22, NAP22
brain abundant, membrane attached signal protein 1
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

Hubel P, Urban C, Bergant V, Schneider WM, Knauer B, Stukalov A, Scaturro P, Mann A, Brunotte L, Hoffmann HH, Schoggins JW, Schwemmle M, Mann M, Rice CM, Pichlmair A

Interferon-stimulated genes (ISGs) form the backbone of the innate immune system and are important for limiting intra- and intercellular viral replication and spread. We conducted a mass-spectrometry-based survey to understand the fundamental organization of the innate immune system and to explore the molecular functions of individual ISGs. We identified interactions between 104 ISGs and 1,401 cellular binding partners engaging in ... [more]

Nat. Immunol. Dec. 01, 2018; 20(4);493-502 [Pubmed: 30833792]

Throughput

  • High Throughput

Curated By

  • BioGRID