TAP1
Gene Ontology Biological Process
- antigen processing and presentation of endogenous peptide antigen via MHC class I [IMP]
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- cytosol to ER transport [IMP]
- intracellular transport of viral protein in host cell [IMP]
- peptide transport [IMP]
- transmembrane transport [IBA]
Gene Ontology Molecular Function- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity, coupled to transmembrane movement of substances [IBA]
- MHC class Ib protein binding [IPI]
- TAP1 binding [ISS]
- TAP2 binding [IPI]
- peptide antigen binding [NAS]
- peptide transporter activity [IGI, IMP]
- protein binding [IPI]
- protein homodimerization activity [ISS]
- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity, coupled to transmembrane movement of substances [IBA]
- MHC class Ib protein binding [IPI]
- TAP1 binding [ISS]
- TAP2 binding [IPI]
- peptide antigen binding [NAS]
- peptide transporter activity [IGI, IMP]
- protein binding [IPI]
- protein homodimerization activity [ISS]
Gene Ontology Cellular Component
CYB5B
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
Interferon-stimulated genes (ISGs) form the backbone of the innate immune system and are important for limiting intra- and intercellular viral replication and spread. We conducted a mass-spectrometry-based survey to understand the fundamental organization of the innate immune system and to explore the molecular functions of individual ISGs. We identified interactions between 104 ISGs and 1,401 cellular binding partners engaging in ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
CYB5B TAP1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.5759 | BioGRID | 3228146 |
Curated By
- BioGRID