CHS2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MYO2
Gene Ontology Biological Process
- Golgi inheritance [IMP]
- budding cell apical bud growth [IMP]
- establishment of mitotic spindle orientation [IMP, IPI]
- membrane addition at site of cytokinesis [IEP, IGI, IMP]
- mitochondrion inheritance [IGI, IMP, IPI]
- peroxisome inheritance [IMP, IPI]
- unidimensional cell growth [IMP]
- vacuole inheritance [IGI, IMP, IPI]
- vesicle transport along actin filament [IEP, IMP]
- vesicle-mediated transport [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Cell polarity protein Spa2 coordinates Chs2 incorporation at the division site in budding yeast.
Deposition of additional plasma membrane and cargoes during cytokinesis in eukaryotic cells must be coordinated with actomyosin ring contraction, plasma membrane ingression and extracellular matrix remodelling. The process by which the secretory pathway promotes specific incorporation of key factors into the cytokinetic machinery is poorly understood. Here, we show that cell polarity protein Spa2 interacts with actomyosin ring components during ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CHS2 MYO2 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.3127 | BioGRID | 1920133 |
Curated By
- BioGRID