RAB10
Gene Ontology Biological Process
- GTP catabolic process [IBA]
- Golgi to plasma membrane protein transport [ISS]
- Golgi to plasma membrane transport [ISS]
- Rab protein signal transduction [IBA]
- antigen processing and presentation [IMP]
- axonogenesis [ISS]
- basolateral protein localization [ISS]
- cellular response to insulin stimulus [IBA, ISS]
- endoplasmic reticulum tubular network organization [IMP]
- endosomal transport [IMP]
- establishment of neuroblast polarity [ISS]
- establishment of protein localization to endoplasmic reticulum membrane [IMP]
- establishment of protein localization to membrane [IMP]
- intracellular protein transport [IBA]
- membrane organization [TAS]
- polarized epithelial cell differentiation [ISS]
- protein localization to plasma membrane [IBA, ISS]
- protein secretion [IBA]
- regulation of exocytosis [IBA]
- vesicle docking involved in exocytosis [IBA]
- vesicle-mediated transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- cytoplasmic vesicle membrane [TAS]
- endoplasmic reticulum membrane [IDA]
- endoplasmic reticulum tubular network [IDA]
- endosome [IDA]
- endosome membrane [IBA]
- exocyst [ISS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- insulin-responsive compartment [IDA]
- plasma membrane [IDA]
- primary cilium [IDA]
- recycling endosome [IDA]
- trans-Golgi network [ISS]
BAG6
Gene Ontology Biological Process
- brain development [ISS]
- embryo development [ISS]
- internal peptidyl-lysine acetylation [IDA]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISS]
- kidney development [ISS]
- lung development [ISS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- negative regulation of proteolysis [ISS]
- protein stabilization [ISS]
- spermatogenesis [ISS]
- synaptonemal complex assembly [ISS]
- tail-anchored membrane protein insertion into ER membrane [IDA]
- ubiquitin-dependent protein catabolic process [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Cytoplasmic control of Rab family small GTPases through BAG6.
Rab family small GTPases are master regulators of distinct steps of intracellular vesicle trafficking in eukaryotic cells. GDP-bound cytoplasmic forms of Rab proteins are prone to aggregation due to the exposure of hydrophobic groups but the machinery that determines the fate of Rab species in the cytosol has not been elucidated in detail. In this study, we find that BAG6 ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID