SERPINA1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
LMAN1
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [TAS]
- Golgi organization [IMP]
- blood coagulation [TAS]
- cellular protein metabolic process [TAS]
- early endosome to Golgi transport [IMP]
- positive regulation of organelle organization [IMP]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
- protein exit from endoplasmic reticulum [IMP]
- protein folding [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The E3 ubiquitin ligase MARCH2 regulates ERGIC3-dependent trafficking of secretory proteins.
The E3 ubiquitin ligase membrane-associated ring-CH-type finger 2 (MARCH2) is known to be involved in intracellular vesicular trafficking, but its role in the early secretory pathway between the endoplasmic reticulum (ER) and Golgi compartments is largely unknown. Human ER-Golgi intermediate compartment protein 2 (ERGIC2) and ERGIC3 are orthologs of Erv41 and Erv46 in yeast, proteins that form a heteromeric complex, ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID