BAIT
HAVCR1
HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1
hepatitis A virus cellular receptor 1
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
GABARAP
ATG8A, GABARAP-a, MM46, HT004
GABA(A) receptor-associated protein
GO Process (7)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Tctex-1, a novel interaction partner of Kidney Injury Molecule-1, is required for efferocytosis.
Kidney injury molecule-1 (KIM-1) is a phosphatidylserine receptor that is specifically upregulated on proximal tubular epithelial cells (PTECs) during acute kidney injury and mitigates tissue damage by mediating efferocytosis (the phagocytic clearance of apoptotic cells). The signaling molecules that regulate efferocytosis in TECs are not well understood. Using a yeast two-hybrid screen, we identified the dynein light chain protein, Tctex-1, ... [more]
J. Cell. Physiol. Dec. 01, 2017; 233(10);6877-6895 [Pubmed: 29693725]
Throughput
- High Throughput
Curated By
- BioGRID