BAIT
BASP1
NAP22
brain abundant, membrane attached signal protein 1
GO Process (1)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Rattus norvegicus
PREY
CAMK2A
PK2CDD, PKCCD
calcium/calmodulin-dependent protein kinase II alpha
GO Process (13)
GO Function (8)
GO Component (8)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [ISO, ISS]
- calcium ion transport [ISO, ISS]
- ionotropic glutamate receptor signaling pathway [IDA]
- peptidyl-serine phosphorylation [IDA, ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of calcium ion transport [ISO, ISS]
- positive regulation of cardiac muscle cell apoptotic process [ISO, ISS]
- protein autophosphorylation [IDA, IMP, ISO]
- protein phosphorylation [IDA, IMP, ISO]
- regulation of mitochondrial membrane permeability involved in apoptotic process [ISO, ISS]
- regulation of neuronal synaptic plasticity [ISO, ISS]
- regulation of neurotransmitter secretion [ISO, ISS]
- response to ischemia [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interaction of dynamin I with NAP-22, a neuronal protein enriched in the presynaptic region.
Neurons have well-developed membrane microdomains called "rafts" that are recovered as a detergent-resistant low-density membrane microdomain fraction (DRM). NAP-22 is one of the major protein components of neuronal DRM and localizes in the presynaptic region. In order to know the role of NAP-22 in the synaptic transmission, NAP-22 binding proteins in the cytosol were searched with an affinity screening with ... [more]
Neurosci. Lett. Dec. 14, 2017; 675();59-63 [Pubmed: 29604406]
Throughput
- High Throughput
Curated By
- BioGRID