BIN1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
BECN1
Gene Ontology Biological Process
- CVT pathway [IBA]
- autophagic vacuole assembly [IBA]
- cellular defense response [TAS]
- cellular response to nitrogen starvation [IBA]
- cytokinesis [IMP]
- late endosome to vacuole transport [IBA]
- negative regulation of apoptotic process [TAS]
- nucleophagy [IBA]
- positive regulation of autophagy [IMP]
- positive regulation of mitochondrion degradation [IMP]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Bin1 antibody lowers the expression of phosphorylated Tau in Alzheimer's disease.
Alzheimer's disease (AD) is an irreversible, progressive brain disorder responsible for memory loss leading to the inability to carry out the simplest tasks. AD is one of the leading causes of death in the United States. As yet there are no effective medications to treat this debilitating disease. In recent years, a human gene called bridging integrator 1 (BIN1) has emerged ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID