UTRN
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- contractile ring [ISO]
- cortical actin cytoskeleton [ISO]
- cytoplasm [ISO]
- dystrophin-associated glycoprotein complex [IDA]
- extracellular vesicular exosome [ISO]
- filopodium [ISO]
- filopodium membrane [ISO]
- growth cone [ISO]
- neuromuscular junction [IDA, ISO]
- nucleoplasm [ISO]
- plasma membrane [ISO]
- protein complex [ISO]
- sarcolemma [IDA]
- synapse [IDA]
NDE1
Gene Ontology Biological Process
- centrosome duplication [IMP]
- centrosome localization [IBA]
- cerebral cortex development [IGI, ISO]
- chromosome segregation [IBA]
- establishment of chromosome localization [IBA, ISO]
- establishment of mitotic spindle orientation [IBA, ISO]
- forebrain development [IMP]
- microtubule nucleation [IDA]
- microtubule organizing center organization [IMP]
- mitotic centrosome separation [IBA]
- neuroblast proliferation [IMP]
- neuron migration [IMP]
- vesicle transport along microtubule [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Three-dimensional regulation of radial glial functions by Lis1-Nde1 and dystrophin glycoprotein complexes.
Radial glial cells (RGCs) are distinctive neural stem cells with an extraordinary slender bipolar morphology and dual functions as precursors and migration scaffolds for cortical neurons. Here we show a novel mechanism by which the Lis1-Nde1 complex maintains RGC functions through stabilizing the dystrophin/dystroglycan glycoprotein complex (DGC). A direct interaction between Nde1 and utrophin/dystrophin allows for the assembly of a ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NDE1 UTRN | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID