BAIT
DUSP26
DUSP24, LDP-4, MKP8, NATA1, SKRP3
dual specificity phosphatase 26 (putative)
GO Process (7)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- negative regulation of ERK1 and ERK2 cascade [IDA]
- negative regulation of protein kinase activity by regulation of protein phosphorylation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- peptidyl-tyrosine dephosphorylation [IMP]
- positive regulation of cell adhesion [IMP]
- positive regulation of peptidyl-serine dephosphorylation [IDA]
- protein dephosphorylation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AFG3L2
SCA28, SPAX5
AFG3-like AAA ATPase 2
GO Process (0)
GO Function (2)
GO Component (1)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID