BAIT
PTPRM
PTPRL1, R-PTP-MU, RPTPM, RPTPU, hR-PTPu
protein tyrosine phosphatase, receptor type, M
GO Process (11)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- homophilic cell adhesion via plasma membrane adhesion molecules [IDA]
- negative regulation of angiogenesis [IMP]
- negative regulation of endothelial cell migration [IMP]
- negative regulation of endothelial cell proliferation [IMP]
- neuron projection development [IDA, IMP]
- peptidyl-tyrosine dephosphorylation [IDA]
- protein dephosphorylation [IDA]
- response to drug [IDA]
- retina layer formation [IMP]
- retinal ganglion cell axon guidance [IDA]
- signal transduction [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ATAD3A
RP5-832C2.1
ATPase family, AAA domain containing 3A
GO Process (2)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID