BAIT
DUSP7
MKPX, PYST2
dual specificity phosphatase 7
GO Process (18)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- MyD88-independent toll-like receptor signaling pathway [TAS]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- inactivation of MAPK activity [IDA]
- innate immune response [TAS]
- negative regulation of MAP kinase activity [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- peptidyl-tyrosine dephosphorylation [IDA]
- stress-activated MAPK cascade [TAS]
- toll-like receptor 10 signaling pathway [TAS]
- toll-like receptor 2 signaling pathway [TAS]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor 5 signaling pathway [TAS]
- toll-like receptor 9 signaling pathway [TAS]
- toll-like receptor TLR1:TLR2 signaling pathway [TAS]
- toll-like receptor TLR6:TLR2 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytosol [IDA]
- nucleoplasm [TAS]
Homo sapiens
PREY
ATP2C1
ATP2C1A, BCPM, HHD, PMR1, SPCA1, hSPCA1, HUSSY-28
ATPase, Ca++ transporting, type 2C, member 1
GO Process (15)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- Golgi calcium ion homeostasis [IMP]
- Golgi calcium ion transport [IMP]
- actin cytoskeleton reorganization [IMP]
- calcium ion transmembrane transport [IDA, IMP]
- calcium ion transport [IDA, IMP]
- calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [IMP]
- cellular calcium ion homeostasis [IDA, IMP]
- cellular manganese ion homeostasis [IDA]
- epidermis development [IMP]
- ion transmembrane transport [TAS]
- manganese ion transmembrane transport [IDA]
- manganese ion transport [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- signal transduction [IMP]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID