BAIT
TPTE
CT44, PTEN2
transmembrane phosphatase with tensin homology
GO Process (3)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Homo sapiens
PREY
ATP6V1H
MSTP042, NBP1, SFD, SFDalpha, SFDbeta, VMA13, CGI-11
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
GO Process (13)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- ATP catabolic process [NAS]
- ATP hydrolysis coupled proton transport [NAS]
- cellular iron ion homeostasis [TAS]
- endocytosis [IDA]
- insulin receptor signaling pathway [TAS]
- interaction with host [TAS]
- phagosome maturation [TAS]
- regulation of catalytic activity [NAS]
- regulation of defense response to virus by virus [TAS]
- transferrin transport [TAS]
- transmembrane transport [TAS]
- vacuolar acidification [NAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID