BAIT
DUSP19
DUSP17, LMWDSP3, SKRP1, TS-DSP1
dual specificity phosphatase 19
GO Process (9)
GO Function (5)
GO Component (0)
Gene Ontology Biological Process
- JNK cascade [IBA]
- negative regulation of JNK cascade [ISS]
- negative regulation of JUN kinase activity [ISS]
- negative regulation of protein kinase activity [ISS]
- positive regulation of JNK cascade [ISS]
- positive regulation of JUN kinase activity [ISS]
- positive regulation of MAPK cascade [ISS]
- positive regulation of protein kinase activity [ISS]
- protein dephosphorylation [IBA]
Homo sapiens
PREY
CCT6B
CCT-zeta-2, CCTZ-2, Cctz2, TCP-1-zeta-2, TSA303
chaperonin containing TCP1, subunit 6B (zeta 2)
GO Process (3)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID