BAIT
DUSP22
JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX, RP11-328C17.1
dual specificity phosphatase 22
GO Process (9)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
- apoptotic process [TAS]
- cell proliferation [TAS]
- inactivation of MAPK activity [TAS]
- multicellular organismal development [TAS]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of JNK cascade [IBA]
- protein dephosphorylation [IBA]
- regulation of cell proliferation [IBA]
- transforming growth factor beta receptor signaling pathway [IBA]
Gene Ontology Molecular Function
Homo sapiens
PREY
NSF
SKD2
N-ethylmaleimide-sensitive factor
GO Process (10)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [ISS]
- Golgi to plasma membrane protein transport [IBA]
- Golgi vesicle docking [IBA]
- exocytosis [TAS]
- intra-Golgi vesicle-mediated transport [IBA]
- plasma membrane fusion [TAS]
- positive regulation of receptor recycling [IDA]
- regulation of exocytosis [ISS]
- synaptic transmission [TAS]
- vesicle-mediated transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID