BAIT
MTMR4
FYVE-DSP2, ZFYVE11
myotubularin related protein 4
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- peptidyl-tyrosine dephosphorylation [TAS]
- phosphatidylinositol biosynthetic process [TAS]
- phospholipid metabolic process [TAS]
- protein dephosphorylation [TAS]
- small molecule metabolic process [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PRPS1
ARTS, CMTX5, DFN2, DFNX1, PPRibP, PRS-I, PRSI, RP11-540N4.1
phosphoribosyl pyrophosphate synthetase 1
GO Process (9)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
- 5-phosphoribose 1-diphosphate biosynthetic process [TAS]
- carbohydrate metabolic process [TAS]
- hypoxanthine biosynthetic process [IMP]
- nervous system development [IMP]
- purine nucleobase metabolic process [IMP]
- purine nucleotide biosynthetic process [IMP]
- pyrimidine nucleotide biosynthetic process [NAS]
- small molecule metabolic process [TAS]
- urate biosynthetic process [IMP]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID