BAIT
PTPN3
PTP-H1, PTPH1, RP11-18A3.3
protein tyrosine phosphatase, non-receptor type 3
GO Process (6)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- negative regulation of membrane protein ectodomain proteolysis [IMP]
- negative regulation of mitotic cell cycle [IDA]
- peptidyl-tyrosine dephosphorylation [IDA, TAS]
- protein dephosphorylation [IDA]
- regulation of membrane depolarization during action potential [IDA]
- regulation of sodium ion transmembrane transporter activity [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RPS17
DBA4, RPS17L, RPS17L1, RPS17L2, S17
ribosomal protein S17
GO Process (17)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- erythrocyte homeostasis [IMP]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- rRNA processing [IMP]
- ribosomal small subunit assembly [IBA]
- ribosomal small subunit biogenesis [IMP]
- translation [IC, TAS]
- translational elongation [IBA, TAS]
- translational initiation [NAS, TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID