BAIT
PTPRU
FMI, PCP-2, PTP, PTP-J, PTP-PI, PTP-RO, PTPPSI, PTPRO, PTPU2, R-PTP-PSI, R-PTP-U, hPTP-J
protein tyrosine phosphatase, receptor type, U
GO Process (9)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- canonical Wnt signaling pathway [IDA]
- cell adhesion [NAS]
- negative regulation of cell migration [IDA]
- negative regulation of cell proliferation [IDA]
- peptidyl-tyrosine dephosphorylation [IDA, IMP, NAS]
- protein dephosphorylation [IDA]
- protein localization to cell surface [IDA]
- single organismal cell-cell adhesion [IDA]
- transmembrane receptor protein tyrosine phosphatase signaling pathway [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
UBE3C
HECTH2, tcag7.998
ubiquitin protein ligase E3C
GO Process (2)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID