BAIT
PTPN23
HD-PTP, HDPTP, PTP-TD14
protein tyrosine phosphatase, non-receptor type 23
GO Process (7)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- cilium morphogenesis [IMP]
- negative regulation of epithelial cell migration [IMP]
- peptidyl-tyrosine dephosphorylation [IMP]
- positive regulation of adherens junction organization [IMP]
- positive regulation of early endosome to late endosome transport [IMP]
- positive regulation of homophilic cell adhesion [IMP]
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
USP11
UHX1, RP4-659F15.2
ubiquitin specific peptidase 11
GO Process (3)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID