BAIT
GHSR
growth hormone secretagogue receptor
GO Process (13)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA]
- actin polymerization or depolymerization [IDA]
- adult feeding behavior [ISS]
- decidualization [IDA]
- growth hormone secretion [TAS]
- hormone-mediated signaling pathway [IDA]
- negative regulation of inflammatory response [IDA]
- negative regulation of interleukin-1 beta production [IDA]
- negative regulation of interleukin-6 biosynthetic process [IDA]
- negative regulation of tumor necrosis factor biosynthetic process [IDA]
- positive regulation of appetite [ISS]
- positive regulation of multicellular organism growth [IMP]
- response to hormone [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GHSR
growth hormone secretagogue receptor
GO Process (13)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA]
- actin polymerization or depolymerization [IDA]
- adult feeding behavior [ISS]
- decidualization [IDA]
- growth hormone secretion [TAS]
- hormone-mediated signaling pathway [IDA]
- negative regulation of inflammatory response [IDA]
- negative regulation of interleukin-1 beta production [IDA]
- negative regulation of interleukin-6 biosynthetic process [IDA]
- negative regulation of tumor necrosis factor biosynthetic process [IDA]
- positive regulation of appetite [ISS]
- positive regulation of multicellular organism growth [IMP]
- response to hormone [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons.
The truncated non-signaling ghrelin receptor growth hormone secretagogue R1b (GHS-R1b) has been suggested to simply exert a dominant negative role in the trafficking and signaling of the full and functional ghrelin receptor GHS-R1a. Here we reveal a more complex modulatory role of GHS-R1b. Differential co-expression of GHS-R1a and GHS-R1b, both in HEK-293T cells and in striatal and hippocampal neurons in ... [more]
J. Biol. Chem. Jun. 17, 2016; 291(25);13048-62 [Pubmed: 27129257]
Throughput
- Low Throughput
Additional Notes
- bioluminescence resonance energy transfer
Curated By
- BioGRID