BAIT
COMP
TSP5
cartilage oligomeric matrix protein
GO Process (4)
GO Function (9)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PRDX2
Tdpx1
peroxiredoxin 2
GO Process (21)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- T cell proliferation [ISO]
- activation of MAPK activity [ISO]
- cellular response to oxidative stress [ISO]
- homeostasis of number of cells [ISO]
- hydrogen peroxide catabolic process [ISO]
- hydrogen peroxide metabolic process [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of T cell differentiation [ISO]
- negative regulation of extrinsic apoptotic signaling pathway [ISO]
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- negative regulation of lipopolysaccharide-mediated signaling pathway [ISO]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of reactive oxygen species metabolic process [ISO]
- positive regulation of blood coagulation [ISO]
- regulation of apoptotic process [ISO]
- regulation of hydrogen peroxide metabolic process [ISO]
- removal of superoxide radicals [ISO]
- respiratory burst involved in inflammatory response [ISO]
- response to lipopolysaccharide [ISO]
- response to oxidative stress [IMP, ISO]
- thymus development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity.
Vascular smooth muscle cells (VSMCs) are highly phenotypically plastic, and loss of the contractile phenotype in VSMCs has been recognized at the early onset of the pathology of a variety of vascular diseases. However, the endogenous regulatory mechanism to maintain contractile phenotype in VSMCs remains elusive. Moreover, little has been known about the role of the mitochondrial bioenergetics in terms ... [more]
Cell Death Dis Dec. 04, 2017; 9(6);676 [Pubmed: 29867124]
Throughput
- High Throughput
Curated By
- BioGRID