COMP
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PHB
Gene Ontology Biological Process
- DNA biosynthetic process [ISO]
- cellular response to interleukin-6 [ISO]
- histone deacetylation [ISO]
- negative regulation of androgen receptor signaling pathway [ISO]
- negative regulation of apoptotic process [IMP]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [IMP, ISO]
- negative regulation of glucocorticoid receptor signaling pathway [ISO]
- negative regulation of transcription by competitive promoter binding [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- organ regeneration [IEP]
- osteoblast differentiation [ISO]
- ovarian follicle atresia [IEP]
- ovarian follicle development [IEP]
- positive regulation of transcription, DNA-templated [ISO]
- progesterone receptor signaling pathway [ISO]
- regulation of transcription, DNA-templated [ISO]
- response to cytokine [IEP]
- response to drug [IEP]
- response to ethanol [IEP]
- response to immobilization stress [IEP]
- response to peptide hormone [IEP]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytoplasm [IDA, ISO]
- extracellular vesicular exosome [ISO]
- extrinsic component of mitochondrial outer membrane [IDA]
- integral component of plasma membrane [ISO]
- membrane [ISO]
- mitochondrial crista [IDA]
- mitochondrial inner membrane [ISO]
- mitochondrion [IDA, ISO]
- myelin sheath [ISO]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity.
Vascular smooth muscle cells (VSMCs) are highly phenotypically plastic, and loss of the contractile phenotype in VSMCs has been recognized at the early onset of the pathology of a variety of vascular diseases. However, the endogenous regulatory mechanism to maintain contractile phenotype in VSMCs remains elusive. Moreover, little has been known about the role of the mitochondrial bioenergetics in terms ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID