BAIT
SBF1
CMT4B3, DENND7A, MTMR5, C22:RP4-579N16.2
SET binding factor 1
GO Process (2)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ACIN1
ACINUS, ACN, fSAP152
apoptotic chromatin condensation inducer 1
GO Process (8)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [NAS]
- apoptotic chromosome condensation [IDA]
- apoptotic process [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- erythrocyte differentiation [IEP]
- negative regulation of mRNA splicing, via spliceosome [IDA]
- positive regulation of apoptotic process [IDA]
- positive regulation of monocyte differentiation [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.
The myotubularins are a family of phosphatases that dephosphorylate the phosphatidylinositols phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-phosphate. Several family members are mutated in disease, yet the biological functions of the majority of myotubularins remain unknown. To gain insight into the roles of the individual enzymes, we have used affinity purification coupled to mass spectrometry to identify protein-protein interactions for the myotubularins. The myotubularin ... [more]
Mol. Cell Proteomics Apr. 01, 2015; 14(4);946-60 [Pubmed: 25659891]
Throughput
- High Throughput
Curated By
- BioGRID