BAIT

SMN1

BCD541, GEMIN1, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMNT, T-BCD541, TDRD16A
survival of motor neuron 1, telomeric
Homo sapiens

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs.

Ottesen EW, Singh NN, Luo D, Singh RN

The Survival Motor Neuron (SMN) protein is essential for survival of all animal cells. SMN harbors a nucleic acid-binding domain and plays an important role in RNA metabolism. However, the RNA-binding property of SMN is poorly understood. Here we employ iterative in vitro selection and chemical structure probing to identify sequence and structural motif(s) critical for RNA-SMN interactions. Our results ... [more]

Nucleic Acids Res. Dec. 16, 2017; 46(20);10983-11001 [Pubmed: 30165668]

Throughput

  • Low Throughput

Curated By

  • BioGRID