BAIT

OTUD4

DUBA6, HIN1, HSHIN1
OTU deubiquitinase 4
GO Process (1)
GO Function (2)
GO Component (0)

Gene Ontology Biological Process

Homo sapiens
PREY

GPR158

5330427M13Rik, mKIAA1136, RP23-133B16.1
G protein-coupled receptor 158
GO Process (2)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

Das R, Schwintzer L, Vinopal S, Aguado Roca E, Sylvester M, Oprisoreanu AM, Schoch S, Bradke F, Broemer M

Mechanisms that regulate the formation of membrane-less cellular organelles, such as neuronal RNA granules and stress granules, have gained increasing attention over the past years. These granules consist of RNA and a plethora of RNA-binding proteins. Mutations in RNA-binding proteins have been found in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). By performing pulldown experiments ... [more]

J. Cell. Sci. Jun. 17, 2019; 132(12); [Pubmed: 31138677]

Throughput

  • High Throughput

Curated By

  • BioGRID