BAIT
OTUD4
DUBA6, HIN1, HSHIN1
OTU deubiquitinase 4
GO Process (1)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
MFN2
D630023P19Rik, Fzo, RP23-406N5.4
mitofusin 2
GO Process (9)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- GTP catabolic process [ISO]
- blastocyst formation [IMP]
- camera-type eye morphogenesis [IMP]
- mitochondrial fusion [IMP, ISO]
- mitochondrial membrane organization [ISO]
- mitochondrion localization [ISO]
- negative regulation of Ras protein signal transduction [ISO]
- protein localization to pre-autophagosomal structure [ISO]
- protein targeting to mitochondrion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.
Mechanisms that regulate the formation of membrane-less cellular organelles, such as neuronal RNA granules and stress granules, have gained increasing attention over the past years. These granules consist of RNA and a plethora of RNA-binding proteins. Mutations in RNA-binding proteins have been found in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). By performing pulldown experiments ... [more]
J. Cell. Sci. Jun. 17, 2019; 132(12); [Pubmed: 31138677]
Throughput
- High Throughput
Curated By
- BioGRID