BAIT
OTUD4
DUBA6, HIN1, HSHIN1
OTU deubiquitinase 4
GO Process (1)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
MIB1
DIP-1, E430019M12Rik, Mib, mKIAA1323
mindbomb homolog 1 (Drosophila)
GO Process (10)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- Notch signaling pathway [IMP]
- blood vessel development [IMP]
- heart development [IMP]
- heart looping [IMP]
- in utero embryonic development [IMP]
- negative regulation of neuron differentiation [IMP]
- neural tube formation [IMP]
- positive regulation of endocytosis [IDA]
- protein ubiquitination [IBA]
- somitogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.
Mechanisms that regulate the formation of membrane-less cellular organelles, such as neuronal RNA granules and stress granules, have gained increasing attention over the past years. These granules consist of RNA and a plethora of RNA-binding proteins. Mutations in RNA-binding proteins have been found in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). By performing pulldown experiments ... [more]
J. Cell. Sci. Jun. 17, 2019; 132(12); [Pubmed: 31138677]
Throughput
- High Throughput
Curated By
- BioGRID