BAIT
OTUD4
DUBA6, HIN1, HSHIN1
OTU deubiquitinase 4
GO Process (1)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
TAOK1
2810468K05Rik, AU020252, D130018F14Rik, Map3k16, Markk, Psk2, mKIAA1361, RP23-273P3.2
TAO kinase 1
GO Process (12)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- G2 DNA damage checkpoint [ISO]
- MAPK cascade [IBA]
- activation of MAPKK activity [IBA]
- cellular response to DNA damage stimulus [ISO]
- execution phase of apoptosis [ISO]
- intracellular signal transduction [IBA]
- positive regulation of JNK cascade [ISO]
- positive regulation of protein kinase activity [ISO]
- positive regulation of stress-activated MAPK cascade [ISO]
- protein phosphorylation [IBA, ISO]
- regulation of cytoskeleton organization [ISO]
- response to stress [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.
Mechanisms that regulate the formation of membrane-less cellular organelles, such as neuronal RNA granules and stress granules, have gained increasing attention over the past years. These granules consist of RNA and a plethora of RNA-binding proteins. Mutations in RNA-binding proteins have been found in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). By performing pulldown experiments ... [more]
J. Cell. Sci. Jun. 17, 2019; 132(12); [Pubmed: 31138677]
Throughput
- High Throughput
Curated By
- BioGRID