BAIT

OTUD4

DUBA6, HIN1, HSHIN1
OTU deubiquitinase 4
GO Process (1)
GO Function (2)
GO Component (0)

Gene Ontology Biological Process

Homo sapiens
PREY

AP1M1

AA408894, AP47, Adtm1A, Cltnm, [m]1A, mu1A
adaptor-related protein complex AP-1, mu subunit 1
GO Process (4)
GO Function (1)
GO Component (5)
Mus musculus

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

Das R, Schwintzer L, Vinopal S, Aguado Roca E, Sylvester M, Oprisoreanu AM, Schoch S, Bradke F, Broemer M

Mechanisms that regulate the formation of membrane-less cellular organelles, such as neuronal RNA granules and stress granules, have gained increasing attention over the past years. These granules consist of RNA and a plethora of RNA-binding proteins. Mutations in RNA-binding proteins have been found in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). By performing pulldown experiments ... [more]

J. Cell. Sci. Jun. 17, 2019; 132(12); [Pubmed: 31138677]

Throughput

  • High Throughput

Curated By

  • BioGRID