BAIT

HMGB1

HMG1, HMG3, SBP-1, RP11-550P23.1
high mobility group box 1
GO Process (22)
GO Function (13)
GO Component (7)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.

Barreiro-Alonso A, Lamas-Maceiras M, Garcia-Diaz R, Rodriguez-Belmonte E, Yu L, Pardo M, Choudhary JS, Cerdan ME

High Mobility Group B (HMGB) proteins are involved in cancer progression and in cellular responses to platinum compounds used in the chemotherapy of prostate and ovary cancer. Here we use affinity purification coupled to mass spectrometry (MS) and yeast two-hybrid (Y2H) screening to carry out an exhaustive study of HMGB1 and HMGB2 protein interactions in the context of prostate and ... [more]

Oncotarget Apr. 10, 2018; 9(27);19050-19064 [Pubmed: 29721183]

Throughput

  • High Throughput

Curated By

  • BioGRID