ZTL
Gene Ontology Biological Process
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [IC]
- circadian rhythm [IMP, ISS, TAS]
- entrainment of circadian clock by photoperiod [IMP]
- flower development [IMP]
- proteasomal protein catabolic process [IMP]
- regulation of circadian rhythm [IMP]
- response to red light [IMP]
- ubiquitin-dependent protein catabolic process [TAS]
Gene Ontology Molecular Function
PHYB
Gene Ontology Biological Process
- abscisic acid metabolic process [IMP]
- chromatin organization [IMP]
- circadian regulation of calcium ion oscillation [IMP]
- entrainment of circadian clock [IMP]
- gravitropism [IMP]
- jasmonic acid mediated signaling pathway [IMP]
- photomorphogenesis [IMP]
- photosynthesis [IMP]
- phototropism [IMP]
- red light signaling pathway [IMP]
- regulation of defense response [IMP]
- regulation of seed germination [IMP]
- regulation of transcription, DNA-templated [ISS]
- response to cold [IMP]
- response to far red light [IMP]
- response to low fluence red light stimulus [IMP]
- stomatal complex development [IMP]
- transpiration [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Forward genetic analysis of the circadian clock separates the multiple functions of ZEITLUPE.
The circadian system of Arabidopsis (Arabidopsis thaliana) includes feedback loops of gene regulation that generate 24-h oscillations. Components of these loops remain to be identified; none of the known components is completely understood, including ZEITLUPE (ZTL), a gene implicated in regulated protein degradation. ztl mutations affect both circadian and developmental responses to red light, possibly through ZTL interaction with PHYTOCHROME ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ZTL PHYB | Reconstituted Complex Reconstituted Complex An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator. | Low | - | BioGRID | - | |
| ZTL PHYB | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID