PPP1CA
Gene Ontology Biological Process
- branching morphogenesis of an epithelial tube [IMP]
- cellular process [TAS]
- circadian regulation of gene expression [IDA]
- dephosphorylation [ISS]
- entrainment of circadian clock by photoperiod [IMP]
- female meiotic division [TAS]
- glycogen metabolic process [TAS]
- lung development [IMP]
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [IMP]
- protein dephosphorylation [IDA, ISO, TAS]
- regulation of circadian rhythm [IDA, IMP, ISO]
- regulation of glycogen biosynthetic process [ISO]
- regulation of glycogen catabolic process [ISO]
- regulation of translation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- MLL5-L complex [ISO]
- PTW/PP1 phosphatase complex [ISO]
- cytoplasm [IDA, ISO]
- dendritic spine [ISO]
- extracellular vesicular exosome [ISO]
- glycogen granule [ISO]
- neuron projection [ISO]
- neuronal cell body [ISO]
- nucleoplasm [IDA, ISO]
- nucleus [IDA, ISO]
- perikaryon [ISO]
- plasma membrane [ISO]
- protein phosphatase type 1 complex [ISO]
PPP1CC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.
Heart failure (HF) is a complex disease with a rising prevalence despite advances in treatment. Protein phosphatase 1 (PP1) has long been implicated in HF pathogenesis, but its exact role is both unclear and controversial. Most previous studies measured only the PP1 catalytic subunit (PP1c) without investigating its diverse set of interactors, which confer localization and substrate specificity to the ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PPP1CA PPP1CC | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.7665 | BioGRID | 2672409 |
Curated By
- BioGRID