BAIT
CLUAP1
CFAP22, FAP22
clusterin associated protein 1
GO Process (1)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TPM1
C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA
tropomyosin 1 (alpha)
GO Process (17)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- cardiac muscle contraction [IMP]
- cellular component movement [TAS]
- cellular response to reactive oxygen species [IEP]
- cytoskeleton organization [TAS]
- muscle contraction [TAS]
- muscle filament sliding [ISS, TAS]
- negative regulation of cell migration [ISS]
- positive regulation of ATPase activity [ISS]
- positive regulation of cell adhesion [ISS]
- positive regulation of heart rate by epinephrine [ISS]
- positive regulation of stress fiber assembly [ISS]
- regulation of heart contraction [TAS]
- regulation of muscle contraction [TAS]
- ruffle organization [ISS]
- sarcomere organization [IMP]
- ventricular cardiac muscle tissue morphogenesis [IMP]
- wound healing [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement.
CRISPR/Cas9-mediated gene editing allows manipulation of a gene of interest in its own chromosomal context. When applied to the analysis of protein interactions and in contrast to exogenous expression of a protein, this can be studied maintaining physiological stoichiometry, topology, and context. We have used CRISPR/Cas9-mediated genomic editing to investigate Cluap1/IFT38, a component of the intraflagellar transport complex B (IFT-B). ... [more]
Mol. Cell Proteomics Dec. 01, 2017; 17(7);1285-1294 [Pubmed: 29615496]
Throughput
- High Throughput
Curated By
- BioGRID