BAIT
YWHAZ
14-3-3-zeta, HEL-S-3, HEL4, KCIP-1, YWHAD
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
GO Process (13)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- Golgi reassembly [IMP]
- RNA metabolic process [TAS]
- apoptotic process [TAS]
- blood coagulation [TAS]
- establishment of Golgi localization [IMP]
- gene expression [TAS]
- intrinsic apoptotic signaling pathway [TAS]
- mRNA metabolic process [TAS]
- membrane organization [TAS]
- negative regulation of apoptotic process [TAS]
- platelet activation [TAS]
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FN1
E330027I09, Fn, Fn-1
fibronectin 1
GO Process (19)
GO Function (5)
GO Component (10)
Gene Ontology Biological Process
- calcium-independent cell-matrix adhesion [IDA]
- cell activation [ISO]
- cell adhesion [IDA]
- cell-matrix adhesion [IDA, ISO]
- cell-substrate junction assembly [IDA]
- cellular response to interleukin-1 [ISO]
- cellular response to mercury ion [ISO]
- endodermal cell differentiation [ISO]
- extracellular matrix organization [ISO]
- glial cell migration [ISO]
- integrin activation [ISO]
- negative regulation of apoptotic process [ISO]
- peptide cross-linking [ISO]
- positive regulation of axon extension [IDA]
- positive regulation of cell migration [ISO]
- positive regulation of chemotaxis [ISO]
- positive regulation of peptidase activity [IDA]
- substrate adhesion-dependent cell spreading [ISO]
- wound healing [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical plasma membrane [IDA]
- basal lamina [IDA]
- basement membrane [IDA, ISO]
- blood microparticle [ISO]
- endoplasmic reticulum-Golgi intermediate compartment [ISO]
- extracellular matrix [IDA, ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- fibrinogen complex [ISO]
- proteinaceous extracellular matrix [IDA, TAS]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Elucidation of the 14-3-3? interactome reveals critical roles of RNA-splicing factors during adipogenesis.
Adipogenesis involves a complex signaling network requiring strict temporal and spatial organization of effector molecules. Molecular scaffolds, such as 14-3-3 proteins, facilitate such organization, and we have previously identified 14-3-3? as an essential scaffold in adipocyte differentiation. The interactome of 14-3-3? is large and diverse, and it is possible that novel adipogenic factors may be present within it, but this ... [more]
J. Biol. Chem. Dec. 04, 2017; 293(18);6736-6750 [Pubmed: 29530978]
Throughput
- High Throughput
Curated By
- BioGRID