BAIT
YWHAZ
14-3-3-zeta, HEL-S-3, HEL4, KCIP-1, YWHAD
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
GO Process (13)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- Golgi reassembly [IMP]
- RNA metabolic process [TAS]
- apoptotic process [TAS]
- blood coagulation [TAS]
- establishment of Golgi localization [IMP]
- gene expression [TAS]
- intrinsic apoptotic signaling pathway [TAS]
- mRNA metabolic process [TAS]
- membrane organization [TAS]
- negative regulation of apoptotic process [TAS]
- platelet activation [TAS]
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TGM2
G[a]h, TG2, TGase2, tTG, tTGas, RP23-396G1.2
transglutaminase 2, C polypeptide
GO Process (17)
GO Function (5)
GO Component (10)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [TAS]
- apoptotic cell clearance [ISO]
- blood vessel remodeling [ISO]
- branching involved in salivary gland morphogenesis [IMP]
- isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [ISO]
- negative regulation of endoplasmic reticulum calcium ion concentration [IMP, ISO]
- peptide cross-linking [TAS]
- phospholipase C-activating G-protein coupled receptor signaling pathway [ISA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of cell adhesion [IMP]
- positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [ISO]
- positive regulation of inflammatory response [ISO]
- positive regulation of mitochondrial calcium ion concentration [IMP, ISO]
- positive regulation of smooth muscle cell proliferation [ISO]
- protein homooligomerization [ISO]
- salivary gland cavitation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Elucidation of the 14-3-3? interactome reveals critical roles of RNA-splicing factors during adipogenesis.
Adipogenesis involves a complex signaling network requiring strict temporal and spatial organization of effector molecules. Molecular scaffolds, such as 14-3-3 proteins, facilitate such organization, and we have previously identified 14-3-3? as an essential scaffold in adipocyte differentiation. The interactome of 14-3-3? is large and diverse, and it is possible that novel adipogenic factors may be present within it, but this ... [more]
J. Biol. Chem. Dec. 04, 2017; 293(18);6736-6750 [Pubmed: 29530978]
Throughput
- High Throughput
Curated By
- BioGRID