BAIT
STAU1
PPP1R150, STAU, RP3-470L14.2
staufen double-stranded RNA binding protein 1
GO Process (2)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GCLC
GCL, GCS, GLCL, GLCLC
glutamate-cysteine ligase, catalytic subunit
GO Process (15)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- cell redox homeostasis [IDA]
- cellular nitrogen compound metabolic process [TAS]
- cysteine metabolic process [IDA]
- glutamate metabolic process [IDA]
- glutathione biosynthetic process [IDA, IMP, TAS]
- glutathione derivative biosynthetic process [TAS]
- negative regulation of apoptotic process [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- regulation of blood vessel size [IMP]
- response to heat [IDA]
- response to hormone [IDA]
- response to oxidative stress [IDA]
- small molecule metabolic process [TAS]
- sulfur amino acid metabolic process [TAS]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.
Alternative 3' untranslated regions (3' UTRs) are widespread, but their functional roles are largely unknown. We investigated the function of the long BIRC3 3' UTR, which is upregulated in leukemia. The 3' UTR does not regulate BIRC3 protein localization or abundance but is required for CXCR4-mediated B cell migration. We established an experimental pipeline to study the mechanism of regulation and ... [more]
Mol. Cell Dec. 16, 2018; 74(4);701-712.e9 [Pubmed: 30948266]
Throughput
- High Throughput
Curated By
- BioGRID