BAIT
STAU1
PPP1R150, STAU, RP3-470L14.2
staufen double-stranded RNA binding protein 1
GO Process (2)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NCBP1
CBP80, NCBP, Sto1, RP11-546O6.1
nuclear cap binding protein subunit 1, 80kDa
GO Process (20)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- 7-methylguanosine mRNA capping [IDA, TAS]
- RNA metabolic process [TAS]
- RNA splicing [TAS]
- gene expression [TAS]
- histone mRNA metabolic process [TAS]
- mRNA 3'-end processing [TAS]
- mRNA cleavage [IDA]
- mRNA export from nucleus [IMP, TAS]
- mRNA metabolic process [TAS]
- mRNA splicing, via spliceosome [TAS]
- ncRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IDA, IMP, TAS]
- positive regulation of mRNA 3'-end processing [IDA]
- positive regulation of viral transcription [TAS]
- regulation of translational initiation [IDA]
- spliceosomal snRNP assembly [TAS]
- termination of RNA polymerase II transcription [TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase II promoter [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.
Alternative 3' untranslated regions (3' UTRs) are widespread, but their functional roles are largely unknown. We investigated the function of the long BIRC3 3' UTR, which is upregulated in leukemia. The 3' UTR does not regulate BIRC3 protein localization or abundance but is required for CXCR4-mediated B cell migration. We established an experimental pipeline to study the mechanism of regulation and ... [more]
Mol. Cell Dec. 16, 2018; 74(4);701-712.e9 [Pubmed: 30948266]
Throughput
- High Throughput
Curated By
- BioGRID