BAIT

BIRC3

AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2
baculoviral IAP repeat containing 3
Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

Lee SH, Mayr C

Alternative 3' untranslated regions (3' UTRs) are widespread, but their functional roles are largely unknown. We investigated the function of the long BIRC3 3' UTR, which is upregulated in leukemia. The 3' UTR does not regulate BIRC3 protein localization or abundance but is required for CXCR4-mediated B cell migration. We established an experimental pipeline to study the mechanism of regulation and ... [more]

Mol. Cell Dec. 16, 2018; 74(4);701-712.e9 [Pubmed: 30948266]

Throughput

  • Low Throughput

Additional Notes

  • the bait is RNA, i.e. BIRC3 3' UTR

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
BIRC3 SYNCRIP
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
2653269

Curated By

  • BioGRID