NFX1
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- poly(A) RNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- poly(A) RNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [TAS]
Gene Ontology Cellular Component
RPS19
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- erythrocyte differentiation [IMP]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- maturation of SSU-rRNA [IMP]
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]
- monocyte chemotaxis [IDA]
- negative regulation of respiratory burst involved in inflammatory response [IDA]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- nucleolus organization [IMP]
- positive regulation of cellular component movement [TAS]
- positive regulation of respiratory burst involved in inflammatory response [IDA]
- protein tetramerization [IDA]
- rRNA processing [IMP]
- response to extracellular stimulus [TAS]
- ribosomal small subunit assembly [IMP]
- ribosomal small subunit biogenesis [IMP]
- translation [IC, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.
The deubiquitinase USP9X is involved in multiple diseases including neurodegeneration, epilepsy, and various types of tumors by targeting different substrates. In the present study, we aimed to explore the potential substrates of USP9X and performed SILAC-based quantitative proteomics to compare these substrates in USP9X-knockdown and wild-type HeLa cells. We consequently carried out Flag-NFX1-123 tag affinity-based mass spectrometry and confirmed that ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
NFX1 RPS19 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID