BAIT
GABARAPL1
APG8-LIKE, APG8L, ATG8, ATG8B, ATG8L, GEC1
GABA(A) receptor-associated protein like 1
GO Process (4)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ATP1A3
Atpa1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
GO Process (13)
GO Function (6)
GO Component (12)
Gene Ontology Biological Process
- ATP hydrolysis coupled proton transport [TAS]
- adult locomotory behavior [ISO]
- cellular potassium ion homeostasis [ISO]
- cellular sodium ion homeostasis [ISO]
- ionotropic glutamate receptor signaling pathway [ISO]
- memory [ISO]
- potassium ion import [ISO]
- potassium ion transport [IDA]
- response to drug [ISO]
- sodium ion export from cell [ISO]
- sodium ion transmembrane transport [ISS]
- sodium ion transport [IDA]
- visual learning [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.
GABARAPL1 belongs to the small family of GABARAP proteins (including GABARAP, GABARAPL1 and GABARAPL2/GATE-16), one of the two subfamilies of the yeast Atg8 orthologue. GABARAPL1 is involved in the intracellular transport of receptors, via an interaction with tubulin and GABA(A) or kappa opioid receptors, and also participates in autophagy and cell proliferation. In the present study, we identify the HSP90 ... [more]
Biochimie Mar. 01, 2012; 94(3);748-58 [Pubmed: 22120110]
Throughput
- Low Throughput
Additional Notes
- Species of bait is unclear
Curated By
- BioGRID