BAIT
GABARAPL1
APG8-LIKE, APG8L, ATG8, ATG8B, ATG8L, GEC1
GABA(A) receptor-associated protein like 1
GO Process (4)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MAP1B
Mtap1b
microtubule-associated protein 1B
GO Process (30)
GO Function (5)
GO Component (16)
Gene Ontology Biological Process
- axon extension [ISO]
- axonogenesis [ISO]
- cellular process [ISO]
- cellular response to growth factor stimulus [IEP]
- cellular response to peptide hormone stimulus [IEP]
- dendrite development [ISO]
- developmental maturation [IEP]
- establishment of monopolar cell polarity [ISO]
- induction of synaptic plasticity by chemical substance [IEP]
- microtubule bundle formation [IDA, ISO]
- mitochondrion transport along microtubule [ISO]
- negative regulation of intracellular transport [ISO]
- negative regulation of microtubule depolymerization [IDA]
- nervous system development [IEP]
- neuron development [IEP]
- peripheral nervous system axon regeneration [IEP]
- positive regulation of axon extension [IMP, ISO]
- positive regulation of microtubule polymerization [IDA]
- positive regulation of neuron differentiation [IMP]
- response to axon injury [IEP]
- response to carbohydrate [IEP]
- response to drug [IEP]
- response to estradiol [IEP]
- response to inorganic substance [IEP]
- response to insecticide [IEP]
- response to mechanical stimulus [IEP]
- response to nutrient levels [IEP]
- response to vitamin A [IEP]
- response to wounding [IEP]
- synapse assembly [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [IDA]
- cell [ISO]
- cytoplasm [ISO]
- cytoskeleton [IDA]
- cytosol [ISO]
- dendrite [IDA]
- growth cone [IDA]
- intracellular [ISO]
- microtubule associated complex [IDA]
- neuronal cell body [IDA]
- neuronal postsynaptic density [ISO]
- perikaryon [IDA]
- perinuclear region of cytoplasm [IDA]
- photoreceptor outer segment [ISO]
- plasma membrane [IDA, ISO]
- postsynaptic density [IDA, ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.
GABARAPL1 belongs to the small family of GABARAP proteins (including GABARAP, GABARAPL1 and GABARAPL2/GATE-16), one of the two subfamilies of the yeast Atg8 orthologue. GABARAPL1 is involved in the intracellular transport of receptors, via an interaction with tubulin and GABA(A) or kappa opioid receptors, and also participates in autophagy and cell proliferation. In the present study, we identify the HSP90 ... [more]
Biochimie Mar. 01, 2012; 94(3);748-58 [Pubmed: 22120110]
Throughput
- Low Throughput
Additional Notes
- Species of bait is unclear
Curated By
- BioGRID