GABARAPL1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
HSP90AB1
Gene Ontology Biological Process
- cellular response to interleukin-4 [ISO]
- cellular response to organic cyclic compound [IEP]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- placenta development [ISO]
- positive regulation of cell size [IMP]
- positive regulation of protein binding [IMP]
- positive regulation of protein import into nucleus, translocation [IMP]
- positive regulation of protein serine/threonine kinase activity [IMP]
- protein folding [TAS]
- regulation of interferon-gamma-mediated signaling pathway [ISO]
- regulation of type I interferon-mediated signaling pathway [ISO]
- response to salt stress [IEP]
- response to unfolded protein [TAS]
Gene Ontology Molecular Function- ATP binding [IDA, TAS]
- CTP binding [IDA]
- GTP binding [IDA]
- MHC class II protein complex binding [ISO]
- UTP binding [IDA]
- dATP binding [IDA]
- double-stranded RNA binding [ISO]
- ion channel binding [IPI]
- kinase binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- sulfonylurea receptor binding [IPI]
- ATP binding [IDA, TAS]
- CTP binding [IDA]
- GTP binding [IDA]
- MHC class II protein complex binding [ISO]
- UTP binding [IDA]
- dATP binding [IDA]
- double-stranded RNA binding [ISO]
- ion channel binding [IPI]
- kinase binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- sulfonylurea receptor binding [IPI]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.
GABARAPL1 belongs to the small family of GABARAP proteins (including GABARAP, GABARAPL1 and GABARAPL2/GATE-16), one of the two subfamilies of the yeast Atg8 orthologue. GABARAPL1 is involved in the intracellular transport of receptors, via an interaction with tubulin and GABA(A) or kappa opioid receptors, and also participates in autophagy and cell proliferation. In the present study, we identify the HSP90 ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID