PDCD6IP
Gene Ontology Biological Process
- apoptotic process [TAS]
- positive regulation of exosomal secretion [ISO]
- positive regulation of extracellular vesicular exosome assembly [ISO]
- regulation of extracellular vesicular exosome assembly [ISO]
- ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [ISO]
- viral budding via host ESCRT complex [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
DRD3
Gene Ontology Biological Process
- G-protein coupled receptor internalization [ISO]
- G-protein coupled receptor signaling pathway [ISO]
- acid secretion [ISO]
- adenylate cyclase-activating dopamine receptor signaling pathway [IDA, ISO]
- adenylate cyclase-inhibiting dopamine receptor signaling pathway [ISO]
- arachidonic acid secretion [ISO]
- behavioral response to cocaine [IMP, ISO]
- cellular calcium ion homeostasis [ISO]
- circadian regulation of gene expression [IMP]
- dopamine receptor signaling pathway [ISO]
- gastric emptying [ISO]
- locomotory behavior [IGI, IMP]
- musculoskeletal movement, spinal reflex action [IMP]
- negative regulation of adenylate cyclase activity [ISO]
- negative regulation of blood pressure [IMP]
- negative regulation of dopamine receptor signaling pathway [IGI]
- negative regulation of oligodendrocyte differentiation [IDA]
- negative regulation of protein kinase B signaling [IMP]
- negative regulation of protein secretion [ISO]
- negative regulation of sodium:proton antiporter activity [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cytokinesis [ISO]
- positive regulation of dopamine receptor signaling pathway [IMP]
- positive regulation of mitosis [ISO]
- positive regulation of renal sodium excretion [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- prepulse inhibition [ISO]
- regulation of blood volume by renin-angiotensin [IGI, IMP]
- regulation of cAMP metabolic process [ISO]
- regulation of circadian sleep/wake cycle, sleep [ISO]
- regulation of dopamine secretion [IMP]
- regulation of lipid metabolic process [IMP]
- regulation of locomotion [ISO]
- regulation of locomotion involved in locomotory behavior [ISO]
- regulation of multicellular organism growth [IMP]
- response to amphetamine [IGI]
- response to cocaine [IMP]
- response to drug [ISO]
- response to ethanol [IMP]
- response to histamine [ISO]
- response to morphine [IMP]
- synaptic transmission [IDA]
- synaptic transmission, dopaminergic [ISO]
- visual learning [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
ALG-2 interacting protein AIP1: a novel link between D1 and D3 signalling.
Dopamine signalling is a critically important process in the human brain that controls mood, cognition and motor activity. In order to gain detailed insight into this signalling pathway at the molecular level, we carried out yeast two-hybrid screens with D1-like (D1, D5) and D2-like (D2, D3, D4) dopamine receptors and identified 11 dopamine receptor interacting proteins (DRIPs). Using the C-terminal ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID