PPP1R9B
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MYO5A
Gene Ontology Biological Process
- actin filament-based movement [IDA, ISO]
- anagen [IMP]
- cellular response to insulin stimulus [IMP]
- developmental pigmentation [IMP]
- endoplasmic reticulum localization [IMP]
- exocytosis [IMP]
- insulin secretion [IMP]
- locomotion involved in locomotory behavior [IMP]
- long-chain fatty acid biosynthetic process [IMP]
- melanin biosynthetic process [IMP]
- melanin metabolic process [IMP]
- melanocyte differentiation [IMP]
- melanosome localization [IMP]
- melanosome transport [IDA, IMP]
- metabolic process [ISO]
- myelination [IMP]
- neuromuscular process controlling balance [IMP]
- odontogenesis [IDA]
- pigmentation [IMP, ISA]
- post-Golgi vesicle-mediated transport [ISO]
- protein localization to plasma membrane [IMP]
- regulation of exocytosis [ISO]
- regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [IMP]
- secretory granule localization [IMP, ISO]
- synapse organization [IMP]
- synaptic transmission [IMP]
- vesicle transport along actin filament [ISO, TAS]
- vesicle-mediated transport [IMP]
- visual perception [IMP]
Gene Ontology Molecular Function- ATP binding [ISO]
- ATP-dependent protein binding [ISO]
- Rab GTPase binding [IPI, ISO]
- SNARE binding [ISO]
- actin binding [IDA]
- calcium ion binding [IDA]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- microfilament motor activity [IDA, ISO]
- motor activity [IDA, ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein dimerization activity [ISO]
- protein heterodimerization activity [ISO]
- syntaxin-1 binding [ISO]
- ATP binding [ISO]
- ATP-dependent protein binding [ISO]
- Rab GTPase binding [IPI, ISO]
- SNARE binding [ISO]
- actin binding [IDA]
- calcium ion binding [IDA]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- microfilament motor activity [IDA, ISO]
- motor activity [IDA, ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein dimerization activity [ISO]
- protein heterodimerization activity [ISO]
- syntaxin-1 binding [ISO]
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- actin filament [ISO]
- actomyosin [IDA]
- actomyosin, myosin complex part [ISO]
- axon [ISO]
- cell [IMP]
- cytoplasm [IDA, ISO]
- cytosol [ISO]
- early endosome [ISO]
- endoplasmic reticulum [ISO]
- extracellular vesicular exosome [ISO]
- filopodium tip [ISO]
- insulin-responsive compartment [IDA]
- intermediate filament [IDA]
- late endosome [ISO]
- lysosome [ISO]
- melanosome [IDA]
- membrane [ISO]
- microtubule plus-end [IDA]
- myosin complex [IDA]
- neuron projection [ISO]
- neuronal cell body [IDA, ISO]
- peroxisome [ISO]
- photoreceptor outer segment [IDA]
- recycling endosome [ISO]
- ruffle [ISO]
- secretory granule [IDA, ISO]
- synaptic vesicle [ISO]
- vesicle [ISO]
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach.
Spinophilin regulates excitatory postsynaptic function and morphology during development by virtue of its interactions with filamentous actin, protein phosphatase 1, and a plethora of additional signaling proteins. To provide insight into the roles of spinophilin in mature brain, we characterized the spinophilin interactome in subcellular fractions solubilized from adult rodent striatum by using a shotgun proteomics approach to identify proteins ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PPP1R9B MYO5A | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - | |
| PPP1R9B MYO5A | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID